Copilot for Biomedical Writing

Ask, verify, and refine evidence in real time.


We are Researchers and Developers from




Ask • Verify • Refine
Rapid Evidence Workflow

Ask

From idea to living review

1. Enter your topic.
2. Receive a PRISMA-grade review.
3. Get evidence-based answers to any question on your topic.

Verify

Instant fact-check of every statement

1. Paste your claim.
2. Spot unverified or contradicting data.
3. Review sources in one click.

Refine

Accept fixes, drop in citations

1. Confirm verified claims.
2. Insert citations automatically.
3. Update the document instantly.


Self-Updating Deep Review

Synthory AI performs fully automated processing of biomedical scientific papers.


Our AI platform generates end-to-end systematic reviews with ~90% alignment to peer-reviewed publications.

Layer 1100%86%SPeer-reviewedpublicationSynthory AI86%24%17%GPT-o1Deep ResearchGeminiDeep ResearchComparison report

Examples of Generated Reviews

Our AI-generated research review shows a close match to a peer-reviewed article. To put our AI to the test, we replicated a study from a peer-reviewed journal to see how our results compared to traditional research.

Despite using different methods (manual vs. AI-driven), the results were remarkably similar, showing that AI-driven reviews can effectively mirror traditional systematic reviews. Read the report for more details.

See more our reviews published on Zenodo repository.


Contact us with inquiries or ideas




© Synthory AI. All rights reserved.   Terms of Use   Privacy Policy

Thank you for getting in touch!

Pilot Program

 
1. Participants will receive a biomedical systematic review.
2. We may showcase the generated reviews unless participants request full confidentiality.
3. Participation is subject to approval by Synthory AI.


© Synthory AI. All rights reserved. Terms of Use

Thank you for your participation in our pilot program!
Once your application is approved, we'll be in touch shortly.
Get ready to accelerate your research with comprehensive reviews!

This report provides researchers and medical-affairs teams with actionable insights into antioxidant-based therapeutic strategies for neurodegenerative diseases. Three illustrative findings are highlighted below, drawn from a comprehensive 494-page analysis; additional insights are provided in the full report.

  • TG15‑132, a selective Nox2 inhibitor, reduces ROS and inflammatory gene expression while penetrating the brain effectively—making it a strong candidate for oxidative stress–linked neurodegeneration.

  • ApoE4 expression impairs neuronal mitochondria, reducing ATP and elevating ROS, suggesting the need for mitochondrial‑targeted interventions to counteract ApoE4‑related cognitive decline.

  • Antioxidant therapy in MS patients cut ROS by 15% and reduced lipid peroxidation and DNA oxidation by 41% and 32%, respectively—supporting clinical use to manage oxidative injury and inflammation.

TitleAuthorYearISBN
6603
Records screened
784
Full-text studies included
Jan 2018–Mar 2025
Coverage window
 

Targeting Oxidative Stress in Neurodegenerative Diseases: Report
$19.00

Buy Full Review



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Synthory AI – Terms of Use
Last updated: 11/17/2025
These Terms of Use (“Terms”) govern your access to and use of the Synthory AI products, services, websites, add-ons, and related tools (collectively, the “Service”).By accessing or using the Service, you agree to be bound by these Terms. If you do not agree, you must not use the Service.


1. Who We Are
“Synthory AI”, “we”, “us”, or “our” means Synthory AI, Inc., with its registered address at: 1111B S Governors Ave STE 37643 Dover, DE, 19904 USIf you are entering into these Terms on behalf of an organization, you represent that you have authority to bind that organization, and “you” will refer to that organization.


2. Eligibility
You may use the Service only if:
* You are at least 18 years old (or the age of majority in your jurisdiction);
* You have the legal capacity to enter into a binding contract; and
* You are not barred from using the Service under applicable law.
If you use the Service on behalf of an organization, you confirm that you are authorized to accept these Terms on its behalf.


3. Description of the Service
Synthory AI provides tools that:
* Automatically search, screen, and synthesize biomedical research articles;
* Generate systematic-style, PRISMA-aligned reviews, evidence summaries, tables, and diagrams; and
* May integrate with third-party platforms (e.g., SciSure) as an add-on.
The Service uses artificial intelligence and machine learning (“AI”) models to generate content (“Outputs”). Outputs may contain errors, omissions, or outdated information, and should be independently verified before use.We may update, improve, or modify the Service from time to time.


4. No Medical Advice – Decision Support Only
The Service and Outputs:
* Do not provide medical advice, diagnosis, or treatment;
* Are not intended to replace professional medical judgment, clinical guidelines, or regulatory submissions; and
* Are offered solely as decision-support and research tools.
You must not use the Service:
* To make direct clinical decisions for individual patients;
* For emergency or life-support use; or
* As a substitute for licensed medical professionals or regulatory experts.
You are solely responsible for how you use the Service and Outputs, and for complying with all clinical, ethical, regulatory, and institutional requirements.


5. No Regulatory or GxP Representations
Unless explicitly agreed in a separate signed agreement:* The Service is not validated for GxP, 21 CFR Part 11, EU Annex 11, or other regulatory-compliant use;
* We make no representation that Outputs are suitable for regulatory submissions, labeling, promotional materials, or safety reporting; and
* You are solely responsible for validating any use of the Service in regulated environments and ensuring compliance with all applicable laws and standards.


6. Account Registration and Security
Some features of the Service may require registration of an account or connection via a third-party platform.You agree to:
* Provide accurate, current, and complete information during registration;
* Keep your login credentials confidential and secure; and
* Notify us promptly at [email protected] of any unauthorized access or use of your account.
You are responsible for all activities that occur under your account, whether or not you authorized them.


7. License to Use the Service
Subject to these Terms and any subscription or order form, we grant you a limited, non-exclusive, non-transferable, revocable license to:* Access and use the Service for your internal business, professional, or research purposes; and
* View, download, and use Outputs generated for you in accordance with these Terms and applicable law.
You may not:
* Reverse engineer, decompile, or attempt to extract source code or models from the Service;
* Circumvent or interfere with security, licensing, or usage controls;
* Use the Service to build or train a directly competing service or model, unless explicitly permitted in writing;
* Remove or obscure any proprietary notices; or
* Use the Service for any unlawful or harmful purpose.


8. User Content and Data
You may provide data, documents, prompts, or other materials to the Service (“User Content”).You retain all rights in your User Content. By submitting User Content, you grant us a non-exclusive, worldwide, royalty-free license to:* Use, process, store, and analyze User Content to operate, maintain, and improve the Service; and
* Generate Outputs and related analytics for you.
You represent and warrant that:* You have all necessary rights, permissions, and consents to submit User Content;
* User Content does not infringe any third-party rights; and
* User Content complies with all applicable laws and policies, including data protection laws.
If you handle personal or sensitive data, you are responsible for obtaining any required consents and implementing appropriate safeguards.


9. Confidentiality of Outputs and Non-Distribution
We understand that reviews and reports generated by the Service may be sensitive.Unless you expressly agree otherwise in writing, we will not:* Publicly distribute, publish, or disclose specific Outputs created for you; or
* Use your identifiable reviews or reports as marketing materials without your consent.
We may share Outputs:* With you and your authorized users;
* With our subprocessors and service providers, strictly as needed to provide and support the Service; and
* As required by law, regulation, or valid legal process.
We may also use aggregated, anonymized, and de-identified information derived from User Content and Outputs to maintain, improve, and develop the Service. Such data will not identify you, your organization, or your specific projects.


10. AI-Generated Outputs
The Service generates Outputs using AI models and automated pipelines.You acknowledge and agree that:
* Outputs may be imperfect, incomplete, outdated, or biased;
* Outputs may not reflect the entire state of the scientific literature;
* We do not guarantee the accuracy, completeness, or fitness for your specific purpose; and
* You must independently review and verify Outputs before you rely on them.
Subject to applicable law and third-party rights, you may use Outputs for your internal or external purposes. You are responsible for ensuring that your use of Outputs complies with:* Copyright and license restrictions of any underlying sources;
* Journal or publisher terms;
* Regulatory and institutional rules.
You may not present Outputs as official consensus, regulatory determinations, or human expert opinion without appropriate review and attribution.


11. Fees, Payments, and Trials
If you purchase a paid plan:
* Fees, billing cycles, and payment terms will be set out in your order form, subscription page, or invoice;
* Unless stated otherwise, subscriptions automatically renew at the then-current rates until canceled; and
* You authorize us or our payment processor to charge your chosen payment method for all applicable fees and taxes.
You may cancel automatic renewal according to the instructions provided. Unless required by law or explicitly stated in writing, we do not provide refunds for unused subscription periods or partial months.We may offer free trials or free tiers, which we may modify or discontinue at any time without notice.


12. Acceptable Use
You agree not to use the Service to:
* Violate any law, regulation, or third-party rights;
* Upload or share content that is unlawful, harmful, threatening, abusive, defamatory, obscene, or otherwise objectionable;
* Attempt to re-identify individuals from de-identified or aggregated data without proper rights and permissions;
* Interfere with or disrupt the Service, servers, or networks;
* Introduce malware, viruses, or harmful code; or
* Benchmark, scrape, or harvest the Service in ways that violate fair use or these Terms.
We may suspend or terminate access if we reasonably believe you are violating these Terms or harming the Service or others.


13. Third-Party Services and Integrations
The Service may rely on or integrate with third-party services and platforms (e.g., SciSure, hosting providers, AI model providers).
* Your use of such third-party services is governed by their own terms and privacy policies;
* We do not control and are not responsible for third-party services, their availability, or their performance; and
* We are not liable for any damages or losses caused by third-party services, except as explicitly required by law.


14. Intellectual Property
All rights, title, and interest in and to the Service, including software, algorithms, models, data structures, documentation, and user interfaces, are and will remain the exclusive property of Synthory AI and its licensors.Except as expressly stated in these Terms, no rights are granted to you, by implication or otherwise, in or to any intellectual property owned or controlled by us.You may provide feedback, suggestions, or ideas about the Service (“Feedback”). You agree that we may use Feedback without restriction and without compensation to you.


15. Disclaimers
The Service and all Outputs are provided on an “as is” and “as available” basis.To the fullest extent permitted by law, we disclaim all warranties, express or implied, including:* Warranties of accuracy, completeness, reliability, non-infringement, merchantability, and fitness for a particular purpose;
* Warranties that the Service will be uninterrupted, error-free, secure, or free of harmful components; and
* Any warranties arising out of course of dealing or usage of trade.
You use the Service and Outputs at your own risk.


16. Limitation of Liability
To the maximum extent permitted by law:* Synthory AI and its officers, directors, employees, agents, and affiliates will not be liable for any indirect, incidental, consequential, special, exemplary, or punitive damages, or for any loss of profits, revenue, data, or business opportunities, arising out of or in connection with the Service, Outputs, or these Terms, even if we have been advised of the possibility of such damages; and
* Our total cumulative liability for all claims arising out of or relating to the Service or these Terms will be limited to the amount you paid to us for the Service in the three (3) months immediately preceding the event giving rise to the claim (or, if you are on a free plan, CAD $100).
Some jurisdictions do not allow certain limitations of liability, so some of the above limitations may not apply to you.


17. Indemnification
You agree to indemnify, defend, and hold harmless Synthory AI and its officers, directors, employees, agents, and affiliates from and against any claims, liabilities, damages, losses, and expenses (including reasonable legal fees) arising out of or related to:* Your use of the Service or Outputs;
* Your User Content;
* Your violation of these Terms; or
* Your violation of any law or third-party right.


18. Changes to the Service and Terms
We may modify, update, or discontinue all or part of the Service at any time.We may update these Terms from time to time. When we do, we will update the “Last updated” date above and, where appropriate, notify you by email or in the Service.Your continued use of the Service after updated Terms become effective means you accept the changes. If you do not agree, you must stop using the Service.


19. Term and Termination
These Terms remain in effect while you access or use the Service.We may suspend or terminate your access to the Service, in whole or in part, if:* You materially breach these Terms;
* We reasonably believe your use poses a risk to us, other users, or the public; or
* We are required to do so by law or by a third-party provider.
Upon termination:* Your right to access and use the Service will end;
* Sections that by their nature should survive (e.g., IP ownership, disclaimers, limitation of liability, indemnification, confidentiality) will remain in effect; and
* We may retain data as permitted by law and our Privacy Policy.


20. Governing Law and Dispute Resolution
These Terms are governed by the laws of the State of Delaware, USA,
without regard to its conflict-of-laws rules.
You agree that any dispute arising out of or relating to these Terms
or the Service will be subject to the exclusive jurisdiction of the
state and federal courts located in New Castle County, Delaware, USA, unless applicable law requires otherwise.
Before bringing a formal claim, you agree to attempt to resolve the dispute informally by contacting us at [email protected] and allowing at least 30 days for resolution.


21. Miscellaneous
If any provision of these Terms is held invalid or unenforceable, the remaining provisions will remain in full force and effect.You may not assign or transfer these Terms, by operation of law or otherwise, without our prior written consent. We may assign these Terms in connection with a merger, acquisition, or sale of assets, or by operation of law.Our failure to enforce any right or provision of these Terms will not be deemed a waiver of such right or provision.These Terms constitute the entire agreement between you and Synthory AI regarding the Service and supersede any prior agreements or understandings.


22. Contact Us
If you have questions about these Terms or the Service, please contact us at:* Email: [email protected]
* Website: https://synthory.ai/
* Address: 1111B S Governors Ave STE 37643 Dover, DE, 19904 US



Synthory AI – Privacy Policy
Last updated: 11/17/2025This Privacy Policy explains how Synthory AI (“Synthory AI”, “we”, “us”, or “our”) collects, uses, shares, and protects personal information when you use our websites, products, services, and add-ons (collectively, the “Service”), including the Synthory AI add-on on the SciSure platform.By using the Service, you agree to the collection and use of information in accordance with this Privacy Policy. If you do not agree, please do not use the Service.


1. Who We Are and How to Contact Us
The Service is operated by:Synthory AI, Inc.
A Delaware corporation
1111B S Governors Ave, STE 37643
Dover, DE 19904, USA
For privacy-related questions or requests, you can contact us at:* Email: [email protected]
* Website: https://synthory.ai/
If you are in the EU/EEA or UK, Synthory AI, Inc. is the data “controller” of your personal data, unless otherwise stated in a separate agreement.


2. Scope of This Policy
This Privacy Policy applies to:
* Our website (e.g., synthory.ai),
* Our web app and APIs,
* The Synthory AI add-on on third-party platforms (such as SciSure), and
* Any other services that link to this Privacy Policy.
It does not apply to third-party services we do not control (such as SciSure itself, payment processors, or cloud providers). Their own privacy policies apply.


3. Information We Collect
We collect information in three main ways:
1. Information you provide directly
2. Information we collect automatically
3. Information we receive from third parties
3.1 Information You Provide DirectlyDepending on how you use the Service, you may provide:* Account and contact information* Name, email address, organization, role/title
* Login credentials (e.g., username, hashed password if we manage auth)
* Billing information* Payment method details (processed by a third-party payment processor)
* Billing address, tax details (if applicable)
* User Content and research data* Documents, queries, prompts, topics, notes, and other content you upload or input
* Scientific articles or identifiers you submit for analysis
* Project metadata (e.g., disease area, target, indication)
* Support and communication data* Messages you send to us (support tickets, emails, feedback, surveys)
* Information you provide during calls, demos, or research interviews
3.2 Information We Collect AutomaticallyWhen you use the Service, we may automatically collect:* Usage data* Features used, click paths, pages viewed, timestamps
* Search queries (e.g., topics, keywords)
* Frequency and type of generated reports/reviews
* Log and device information* IP address, browser type, operating system
* Device identifiers, language, time zone
* Error logs, performance data
* Cookies and similar technologies* Session cookies to keep you logged in
* Preference cookies (e.g., language)
* Analytics cookies (e.g., usage metrics, referral source)
You can typically control cookies through your browser settings. Some features may not work properly if cookies are disabled.3.3 Information from Third PartiesWe may receive information from:* SciSure and other integrated platforms* User identifiers, workspace/project IDs
* Documents or metadata you choose to send to Synthory AI via the integration
* Access permissions or roles
* Service providers* Payment processors (e.g., payment status, limited billing info)
* Analytics providers (aggregated usage statistics)
* Public sources* Publicly available contact details (e.g., LinkedIn, conference websites) for outreach to potential customers
* Public scientific content and metadata


4. How We Use Your Information
We use personal information for the following purposes:4.1 To Provide and Operate the Service* Authenticate you and manage your account
* Process your requests and generate reports/reviews
* Provide integrations (e.g., SciSure add-on, APIs)
* Store and display your User Content and Outputs
4.2 To Improve and Develop the Service* Monitor performance and usage patterns
* Debug issues, enhance reliability and speed
* Train and refine our models and pipelines (where permitted)
* Develop new features and tools
Where possible, we use aggregated and/or anonymized data for these purposes.4.3 To Communicate with You* Send service-related emails (e.g., updates, security notices, changes to terms)
* Respond to your questions and support requests
* Send optional newsletters or product updates (you can opt out at any time)
4.4 For Security and Legal Compliance* Detect, prevent, and respond to fraud, abuse, or security threats
* Protect the rights, property, or safety of Synthory AI, our users, or the public
* Comply with legal obligations, court orders, or enforce our Terms of Use
4.5 For Marketing and Business Development* Identify and reach out to potential customers (e.g., via professional contact details)
* Analyze market segments and product fit
* Use de-identified or aggregated data in case studies or metrics (without naming specific customers unless we have consent)
We do not sell personal information in the sense of allowing third parties to use your personal data for their own marketing, as defined by many privacy laws (e.g., CPRA).5. Legal Bases for Processing (EEA/UK Users)If you are in the EEA or UK, we process your personal data under one or more of the following legal bases:* Contract – To provide the Service and fulfill our agreements with you or your organization.
* Legitimate interests – To improve the Service, ensure security, prevent misuse, and grow our business, where these interests are not overridden by your rights.
* Consent – For certain analytics, cookies, or marketing communications, where required.
* Legal obligation – To comply with applicable laws and regulations.
You may withdraw your consent at any time where processing is based on consent, without affecting the lawfulness of processing before withdrawal.


6. How We Share Information
We may share personal information with:6.1 Service Providers (Processors)Trusted third parties who help us run the Service, such as:* Cloud hosting and infrastructure providers
* AI model and processing providers
* Payment processors and billing providers
* Analytics and monitoring tools
* Customer support and email services
These providers process personal data on our behalf and are bound by contractual obligations to protect it and use it only for our specified purposes.6.2 Integration PartnersWhen you connect Synthory AI to platforms like SciSure:* We may receive data from those platforms, as described in section 3.3
* We may send Outputs or related data back into those platforms, at your request
Your use of third-party platforms is governed by their own terms and privacy policies.6.3 Business TransfersIf we are involved in a merger, acquisition, reorganization, sale of assets, or similar transaction, personal information may be transferred as part of that transaction, subject to applicable law.6.4 Legal and SafetyWe may disclose information if we believe in good faith that it is reasonably necessary to:* Comply with any applicable law, regulation, legal process, or governmental request
* Enforce our Terms of Use or other agreements
* Protect the rights, property, or safety of Synthory AI, our users, or others


7. Confidentiality of Reviews and Outputs
We understand that your reviews, reports, and analyses can be sensitive.Unless you explicitly agree otherwise in writing, we:* Do not publicly distribute or publish specific Outputs generated for your account;
* Do not sell your reviews or reports as content to others; and
* Use your content and Outputs for internal improvement and analytics only in an aggregated and/or anonymized form that does not identify you or your organization or reveal the full content of your reviews.
We may, with your permission, use anonymized or redacted samples for case studies or demos.


8. International Data Transfers
We may process and store personal information in countries outside your own, including the United States and Canada.Where required by law (e.g., GDPR), we use appropriate safeguards for international transfers, such as:* Standard Contractual Clauses approved by the European Commission, or
* Other legally recognized transfer mechanisms.
You can contact us for more details about cross-border transfer safeguards.


9. Data Retention
We retain personal information for as long as reasonably necessary to:* Provide the Service to you or your organization,
* Comply with legal, tax, or accounting obligations,
* Resolve disputes, and
* Enforce our agreements.
We may retain aggregated or anonymized data (which cannot be linked back to you) for longer periods for analytics and improvement.If you close your account or request deletion, we will delete or anonymize your personal data within a reasonable period, unless we are required or permitted to retain it for longer (e.g., legal obligations, dispute resolution).


10. Security
We use reasonable technical and organizational measures to protect personal information, such as:* Encrypted connections (HTTPS/TLS)
* Access controls and authentication
* Regular backups and monitoring
* Logical separation of environments
However, no system is completely secure. We cannot guarantee absolute security. You are responsible for maintaining the confidentiality of your account credentials and for promptly notifying us of any suspected unauthorized access.


11. Your Rights
Depending on your jurisdiction, you may have certain rights regarding your personal information, such as:* Access – Request a copy of the personal data we hold about you.
* Correction – Request correction of inaccurate or incomplete data.
* Deletion – Request deletion of your personal data, subject to legal exceptions.
* Restriction – Request we limit the processing of your data in certain circumstances.
* Portability – Request a machine-readable copy of your data where technically feasible.
* Objection – Object to certain processing (e.g., direct marketing, profiling).
* Withdraw consent – Where processing is based on consent, withdraw that consent at any time.
To exercise these rights, please contact us at [email protected].
We may need to verify your identity before completing your request.
If you are in the EEA/UK, you also have the right to lodge a complaint with your local data protection authority.


12. Children’s Privacy
The Service is not directed to children under 16, and we do not knowingly collect personal information from children under 16.If you believe a child under 16 has provided personal data to us, please contact us and we will take steps to delete such information as required by law.


13. Changes to This Policy
We may update this Privacy Policy from time to time. When we do, we will update the “Last updated” date at the top of this page, and where appropriate, notify you by email or in the Service.Your continued use of the Service after any changes become effective means you accept the updated Privacy Policy. If you do not agree, you should stop using the Service.


14. Contact Us
If you have any questions, concerns, or requests about this Privacy Policy or our data practices, you can reach us at:Synthory AI, Inc.
1111B S Governors Ave, STE 37643
Dover, DE 19904, USA
Email: [email protected]
Website: https://synthory.ai/


PRISMA-Aligned Review Add-on for SciSure

You won’t miss key papers or drown in low-quality studies—Synthory AI screens thousands of articles for every review.

  • Systematic review on demand: creates a full review for your topic directly in SciSure.

  • PRISMA-grade: documented search strategy, deduplication, eligibility criteria, and a PRISMA flow diagram.

  • Quality first: filters out low-quality and outdated studies.

  • Clear evidence: shows where studies agree, where they conflict, and key limitations.

  • Ready to use: experimental-model analysis, concise conclusions with citations, references, tables and PRISMA diagram.

Add Synthory AI to SciSure and get reliable, publication-ready evidence.

Preview a sample review:   Open sample · Download PDF



Quick Guide

  • The review settings are automatically chosen based on the available literature.

  • The system searches and analyzes new papers published from January 2018 up to today.

  • Articles published before 2018 are also analyzed to assess scientific progress, identify conflicting results, and evaluate whether previously reported limitations have been addressed.

  • Only publicly available papers are used.


Pricing

Free
1–3 reviews
Number of free reviews depends on laboratory size.

Install the Synthory AI add-on to get access.

Subscription – $500 / month
  • 3 reviews per month
  • PRISMA-aligned systematic reviews
  • Screening of up to 4,000 articles per review
  • Deliverables up to 200 pages per review (PDF, HTML)

A subscription option appears in the add-on once you’ve used your free reviews.

Contact us  
© Synthory AI. All rights reserved.   Terms of Use   Privacy Policy